Replication of the genome during the S phase of the cell cycle increases the DNA dose of newly replicated genes, but in eukaryotic cells, the mRNA expression levels of these genes do not increase ...
Sometimes a replicating cell must choose the lesser of two evils. For example, when a replicating cell is stressed, it may struggle to pair bases against its single-stranded DNA (ssDNA) template, even ...
Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology (IFOM) in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently ...
DNA replication and repair are critical processes that ensure the correct genetic material of a biological system is carried on. DNA continually undergoes a process of replication and division and ...
The replication fork is more than just a means for DNA duplication. It is connected to a checkpoint system that keeps the genome intact and prevents cancer. Aa Aa Aa Eukaryotic genomes are replicated ...
In a study that appears in the journal Cell, scientists from San Francisco-based Gladstone Institutes—including co-first author Megan Ostrowski (left) and senior author Vijay Ramani, PhD ...
This is a preview. Log in through your library . PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, commentaries, perspectives, reviews, ...
PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, commentaries, perspectives, reviews, colloquium papers, and actions of the Academy. In ...
Sixty years after the discovery of DNA's spiraling, ladderlike structure first hinted at the mechanism by which life copies itself, one of the Nobel Prize medals honoring this achievement is up for ...
Sixty years after the discovery of DNA's spiraling, ladder-like structure first hinted at the mechanism by which life copies itself, one of the Nobel Prize medals honoring this achievement is up for ...
Researchers have discovered how a key function of the AND-1 protein helps protect nascent DNA strands from degradation. Researchers from Tokyo Metropolitan University and the FIRC Institute of ...
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