Understanding how cells turn genes on and off is one of biology's most enduring mysteries. Now, a new technology developed by ...

Anyone who studied a little genetics in high school has heard of adenine, thymine, guanine and cytosine -- the A, T, G and C that make up the DNA code. But those are not the whole story. The rise of ...

Human Rho GTPases (of which there are 22 members) comprise a main branch of the Ras superfamily of small GTPases and GDP/GTP-regulated molecular switches. Rho GTPases are activated by the direct ...

Université de Strasbourg and partners report that adding structural variants and small insertion–deletion mutations to single ...

The nucleotide sequences coding for murine complement component C3 have been determined from a cloned genomic DNA fragment and several overlapping cloned complementary DNA fragments. The amino acid ...

Researchers reveal how the alteration of a single nucleotide—the basic building block of DNA—could initiate fragile X syndrome, the most common inherited form of intellectual disability. Researchers ...

Comparison of Outcomes After Fluorouracil-Based Adjuvant Therapy for Stages II and III Colon Cancer Between 1978 to 1995 and 1996 to 2007: Evidence of Stage Migration From the ACCENT Database Although ...

Tenofovir was approved by the Food and Drug Administration (FDA) in October 2001 through an accelerated approval process; it is the first nucleotide analogue reverse-transcriptase inhibitor marketed ...

The information that is carried by the genetic code provides a set of "instructions" for "building" and "maintaining" a living organism. A useful analogy might be to think of the genetic code being ...

Phase 1 data of first-in-class NBD1 stabilizers, SION-719 and SION-451, demonstrated they were generally well tolerated and ...