AI-guided enzyme discovery enables 98.6% breakdown of polyurethane foam in hours

As the use of AI spreads through every industry and becomes more of a part of our lives every day, researchers are also ...

Neural network finds an enzyme that can break down polyurethane

That problem is why, even though we’ve had success finding enzymes that break down common plastics like polyesters and PET, they’re only partial solutions to plastic waste. However, researchers aren’t ...
RMD Open

Joint involvement in VEXAS and non-VEXAS clonal haematopoiesis: two clusters from a multicentre regional cohort

Objective: To describe the joint manifestations associated with clonal haematopoiesis and to compare patients with and ...
Johns Hopkins Medicine

Digestive Enzymes and Digestive Enzyme Supplements

Digestive enzyme supplements have gained popularity for their claims of treating common forms of gut irritation, heartburn and other ailments. But how do digestive enzymes work, and who really needs ...
Antigua Observer Newspaper

The graphs show the effect of temperature on enzyme activity.This enzyme has an optimum temperature of 30 °C.Which graph shows the effect of temperature on the activity of ...

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C&EN

The Role of Protein Side Chains in Enzyme-Activating Conformational Changes: Lessons from Studies on Variant Enzymes

You are free to share (copy and redistribute) this article in any medium or format and to adapt (remix, transform, and build upon) the material for any purpose, even commercially within the parameters ...
Medical Xpress

Targeting enzymes to weaken cancer cells could supercharge prostate cancer treatment

An international study has uncovered a new vulnerability in prostate cancer cells that could help improve treatment for one of the most common cancers affecting men. The research, published in the ...
C&EN

Use of P450 Enzymes for Late-Stage Functionalization in Drug Discovery

Hypha Discovery Limited, 154B Brook Drive, Milton Park, Abingdon OX14 4SD, U.K. Mode of Action Group, Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, ...
PNAS

Distantly related bacteria share a rigid proteome allocation strategy with flexible enzyme kinetics

Contributed by Terence Hwa; received December 27, 2024; accepted March 21, 2025; reviewed by Vickery L. Arcus and Seppe Kuehn ...
Business Wire

Spruce Biosciences Receives U.S. FDA Breakthrough Therapy Designation for Tralesinidase Alfa Enzyme Replacement Therapy (TA-ERT) in Sanfilippo Syndrome Type B (MPS IIIB)

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Spruce Biosciences, Inc. (Nasdaq: SPRB), a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for neurological ...
IEEE

A Survey on Knowledge Graphs: Representation, Acquisition, and Applications

Abstract: Human knowledge provides a formal understanding of the world. Knowledge graphs that represent structural relations between entities have become an increasingly popular research direction ...