Nature

Microarray fabrication with covalent attachment of DNA using Bubble Jet technology

Here we present a method for the fabrication of microarrays in which presynthesized oligonucleotides are ejected onto a glass surface by a Bubble Jet printing device. The oligonucleotides are then ...
IEEE

Segmentation of microarray cDNA spots using MRF-based method

Abstract: Segmentation or separation of spots from the background in cDNA microarray images is one of the earlier steps in gene expression data analysis. Performance of the segmentation method may ...
C&EN

The Surface Science of Microarray Generation–A Critical Inventory

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...
C&EN

Spatial Bias in Antibody Microarrays May Be an Underappreciated Source of Variability

McGill Genome Centre, McGill University, Montreal, Quebec H3A 0G1, Canada Department of Biomedical Engineering, McGill University, Montreal, Quebec H3A 2B4, Canada McGill Genome Centre, McGill ...
Nature

DNA microarrays in drug discovery and development

Most pharmaceuticals sold today have their origin in a biochemistry laboratory. Drug discovery has traditionally started with a biochemical pathway implicated in a pathophysiological process. An ...
IEEE

A Novel Hybrid Symbolic Fuzzy Interval-Based Clustering Approach for Microarray Image Spot Segmentation

Abstract: Microarray image analysis is an algorithmic and analytical approach used in gene expression profiling in the study of biological and zoological taxonomy. Gene expression data is a structured ...