Icotrokinra, a targeted oral peptide that selectively binds the interleukin-23 receptor, is under investigation for the ...

Opioid deprescribing is advised when risks of opioid use outweigh benefits. A tailored, patient-centered plan with gradual dose reduction, monitoring, and support can improve outcomes and reduce harm.

In their review, Bhasin and Snyder (Aug. 7 issue)1 state that most men who receive testosterone preparations are middle-aged or older and have only moderately decreased testosterone ...

Approximately 5 million persons in the United States have psoriasis.1 Most have mild disease covering less than 3% of body-surface area, but approximately one fifth have more extensive involvement ...

Physical therapy is routinely recommended for knee pain attributed to a degenerative meniscal tear, but its efficacy has not ...

The preferred timing of treatment of nonculprit lesions in patients with ST-segment elevation myocardial infarction (STEMI) remains uncertain. A comparison of immediate percutaneous coronary ...

Whether selective decontamination of the digestive tract (SDD) reduces mortality among patients undergoing mechanical ...

Adjunctive glucocorticoids may reduce mortality among patients with severe community-acquired pneumonia (CAP) in ...

A 56-year-old man was admitted to the hospital because of left lower abdominal pain and anemia. He had a 1-year history of recurrent diarrhea and an enterocolonic fistula. A diagnosis was made.

Five-year data from the PARTNER 3 trial showed that among low-risk patients with severe, symptomatic aortic stenosis, ...

The U.S. antitrust paradigm can’t fully counteract the risks posed by health care corporatization. Regulators need robust procompetitive strategies to recenter patients and health as measures of ...

Approaches to early detection of cancer often seem contentious, but the big-picture view is actually one of remarkable consensus. All major guideline groups recommend the Papanicolaou smear, ...